Patterning microscale extracellular matrices to study endothelial and cancer cell interactions in vitro
نویسندگان
چکیده
منابع مشابه
Patterning microscale extracellular matrices to study endothelial and cancer cell interactions in vitro.
The extracellular matrix (ECM) of the tumor niche provides support to residing and migrating cells and presents instructive cues that influence cellular behaviours. The ECM protein fibronectin (Fn) enables vascular network formation, while hyaluronic acid (HA) is known to facilitate breast tumor development. To recapitulate aspects of the tumor microenvironment, we developed systems of spatiall...
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ژورنال
عنوان ژورنال: Lab on a Chip
سال: 2012
ISSN: 1473-0197,1473-0189
DOI: 10.1039/c2lc40819h